N-BENZYLOXYCARBONYL-D-GLUTAMIC ACID ALPHA-BENZYL ESTER
Z-D-glutamic acid 1-benzyl ester
CAS: 65706-99-2
Molecular Formula: C20H21NO6
N-BENZYLOXYCARBONYL-D-GLUTAMIC ACID ALPHA-BENZYL ESTER - Names and Identifiers
| Name | Z-D-glutamic acid 1-benzyl ester |
| Synonyms | Z-GLU-OBZL Z-D-GLU-OBZL Z-D-Glu-OBzl Z-D-GLUTAMIC ACID-OBZL Z-D-GLUTAMIC ACID 1-BENZYL ESTER Z-D-glutamic acid 1-benzyl ester Cbz-D-glutamic acid 1-benzyl ester N-cbz-D-glutamic acid A-benzyl ester N-Cbz-D-glutamic acid alpha-benzyl ester N-CBZ-D-GLUTAMIC ACID ALPHA-BENZYL ESTER N-BENZYLOXYCARBONYL-L-GLUTAMIC ACID ALPHA-BENZYL ESTER N-BENZYLOXYCARBONYL-D-GLUTAMIC ACID ALPHA-BENZYL ESTER N-ALPHA-CARBOBENZOXY-D-GLUTAMIC ACID ALPHA-BENZYL ESTER (4R)-5-(benzyloxy)-4-{[(benzyloxy)carbonyl]amino}-5-oxopentanoic acid (non-preferred name) |
| CAS | 65706-99-2 |
| EINECS | 2017-001-1 |
| InChI | InChI=1/C20H21NO6/c22-18(23)12-11-17(19(24)26-13-15-7-3-1-4-8-15)21-20(25)27-14-16-9-5-2-6-10-16/h1-10,17H,11-14H2,(H,21,25)(H,22,23)/t17-/m1/s1 |
N-BENZYLOXYCARBONYL-D-GLUTAMIC ACID ALPHA-BENZYL ESTER - Physico-chemical Properties
| Molecular Formula | C20H21NO6 |
| Molar Mass | 371.38 |
| Density | 1.268±0.06 g/cm3(Predicted) |
| Melting Point | 98.0 to 102.0 °C |
| Boling Point | 594.3±50.0 °C(Predicted) |
| Specific Rotation(α) | +22.0 to +25.0 deg(C=1, MeOH) |
| Flash Point | 313.2°C |
| Solubility | Soluble in methanol and acetic acid. |
| Vapor Presure | 5.72E-15mmHg at 25°C |
| Appearance | Crystalline powder |
| Color | White to off-white |
| BRN | 5305848 |
| pKa | 4.47±0.10(Predicted) |
| Storage Condition | Sealed in dry,Room Temperature |
| Refractive Index | 1.575 |
| MDL | MFCD00069647 |
N-BENZYLOXYCARBONYL-D-GLUTAMIC ACID ALPHA-BENZYL ESTER - Risk and Safety
| Safety Description | 24/25 - Avoid contact with skin and eyes. |
| WGK Germany | 3 |
| HS Code | 29242990 |
N-BENZYLOXYCARBONYL-D-GLUTAMIC ACID ALPHA-BENZYL ESTER - Introduction
Z-D-glutamic acid 1-benzyl ester is an organic compound. The following is a description of its nature, use, formulation and safety information:
Nature:
-Appearance: The compound is white crystal or crystalline powder.
-Solubility: Soluble in some organic solvents, such as ethanol, dimethyl sulfoxide and chloroform.
-Melting point: The melting point of the compound is about 145-147 degrees Celsius.
-Molecular formula: C16H19NO5
-Molecular Weight: 309.33
-Structure: It contains benzyl and amino acid groups.
Use:
-Chemical reagent: In organic synthesis, it can be used as a chemical reagent, especially suitable for the synthesis of amino acids.
-Drug research: In drug research, it is used as a precursor of anti-tumor drugs, or used to study kinase inhibitors.
Preparation Method:
Z-D-glutamic acid 1-benzyl ester can be prepared by the following steps:
1. Benzyl alcohol and dimethyl carbamate react under alkaline conditions to produce benzylethanolamine.
2. esterification of benzylethanolamine with D-glutamic acid can obtain Z-D-glutamic acid 1-benzyl ester.
Safety Information:
-The compound needs to be handled and used with appropriate laboratory safety measures.
-Avoid contact with skin, eyes and respiratory tract.
-Use personal protective equipment such as lab coats, gloves and protective glasses.
-It should be operated in a well-ventilated place to avoid inhaling its dust or vapor.
-Follow the correct waste disposal procedures to avoid pollution to the environment.
Nature:
-Appearance: The compound is white crystal or crystalline powder.
-Solubility: Soluble in some organic solvents, such as ethanol, dimethyl sulfoxide and chloroform.
-Melting point: The melting point of the compound is about 145-147 degrees Celsius.
-Molecular formula: C16H19NO5
-Molecular Weight: 309.33
-Structure: It contains benzyl and amino acid groups.
Use:
-Chemical reagent: In organic synthesis, it can be used as a chemical reagent, especially suitable for the synthesis of amino acids.
-Drug research: In drug research, it is used as a precursor of anti-tumor drugs, or used to study kinase inhibitors.
Preparation Method:
Z-D-glutamic acid 1-benzyl ester can be prepared by the following steps:
1. Benzyl alcohol and dimethyl carbamate react under alkaline conditions to produce benzylethanolamine.
2. esterification of benzylethanolamine with D-glutamic acid can obtain Z-D-glutamic acid 1-benzyl ester.
Safety Information:
-The compound needs to be handled and used with appropriate laboratory safety measures.
-Avoid contact with skin, eyes and respiratory tract.
-Use personal protective equipment such as lab coats, gloves and protective glasses.
-It should be operated in a well-ventilated place to avoid inhaling its dust or vapor.
-Follow the correct waste disposal procedures to avoid pollution to the environment.
Last Update：2024-04-09 02:00:47
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Product Name: 1-Benzyl N-Cbz-D-glutamate Visit Supplier Webpage Request for quotationCAS: 65706-99-2
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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